This article analyzes the neuropsycholinguistic mechanisms of speech activity and their linguistic interpretation. The speech process, as a complex cognitive and psychological activity of a person, is formed through the combination of brain activity, linguistic units, and communicative functions. The study analyzes the processes of speech production and speech perception based on a neuropsycholinguistic approach, and also emphasizes the linguistic interpretation of the speech process. The results of the article create a theoretical basis for scientific research in the fields of psycholinguistics, neurolinguistics, and linguistics.